Active Site Sequence Representations of Human Kinases Outperform Full Sequence Representations for Affinity Prediction and Inhibitor Generation: 3D Effects in a 1D Model
- Jannis Born
- Tien Huynh
- et al.
- 2021
- J. Chem. Inf. Model.
Publications
This is our catalog of publications authored by IBM researchers, in collaboration with the global research community. It’s an ever-growing body of work that shows why IBM is one of the most important contributors to modern computing.
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59 results for Tien Huynh
In Silico Antibody Mutagenesis for Optimizing Its Binding to Spike Protein of Severe Acute Respiratory Syndrome Coronavirus 2
- Binquan Luan
- Tien Huynh
- 2020
- Journal of Physical Chemistry Letters
Targeting Proteases for Treating COVID-19
- Binquan Luan
- Tien Huynh
- et al.
- 2020
- Journal of Proteome Research
Low-Dose X-ray-Responsive Diselenide Nanocarriers for Effective Delivery of Anticancer Agents
- Lianxue Zhang
- Shitong Zhang
- et al.
- 2020
- ACS AMI
In Silico Exploration of the Molecular Mechanism of Clinically Oriented Drugs for Possibly Inhibiting SARS-CoV-2's Main Protease
- Tien Huynh
- Haoran Wang
- et al.
- 2020
- Journal of Physical Chemistry Letters
Combining docking pose rank and structure with deep learning improves protein−ligand binding mode prediction over a baseline docking approach
- 2020
- J. Chem. Inf. Model.
The web server of IBM's Bioinformatics and Pattern Discovery group: 2004 update
- Tien Huynh
- Isidore Rigoutsos
- 2004
- Nucleic acids research
Dictionary-driven protein annotation
- Isidore Rigoutsos
- Tien Huynh
- et al.
- 2002
- Nucleic acids research
Crystal-structures-guided design of fragment-based drugs for inhibiting the main protease of SARS-CoV-2
- Binquan Luan
- Tien Huynh
- 2021
- Proteins
Structure-Function Analysis of Resistance to Bamlanivimab by SARS-CoV-2 Variants Kappa, Delta, and Lambda
- Shufeng Liu
- Tien Huynh
- et al.
- 2021
- J. Chem. Inf. Model.