Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism
- Gloria Bonuccelli
- Aristotelis Tsirigos
- et al.
- 2014
- Cell Cycle
Publications
This is our catalog of publications authored by IBM researchers, in collaboration with the global research community. It’s an ever-growing body of work that shows why IBM is one of the most important contributors to modern computing.
Date
Featured collections
Popular topics
10 results at Cell Cycle
The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism
- Stephanos Pavlides
- Aristotelis Tsirigos
- et al.
- 2014
- Cell Cycle
Molecular profiling of a lethal tumor microenvironment, as defined by stromal caveolin-1 status in breast cancers
- Agnieszka K. Witkiewicz
- Jessica Kline
- et al.
- 2014
- Cell Cycle
Mitochondria "fuel" breast cancer metabolism: Fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells
- Federica Sotgia
- Diana Whitaker-Menezes
- et al.
- 2014
- Cell Cycle
Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism
- Adam Ertel
- Aristotelis Tsirigos
- et al.
- 2014
- Cell Cycle
Ketones and lactate increase cancer cell "stemness", driving recurrence, metastasis and poor clinical outcome in breast cancer: Achieving personalized medicine via metabolo-genomics
- Ubaldo E. Martinez-Outschoorn
- Marco Prisco
- et al.
- 2014
- Cell Cycle
Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: Evidence for stromal-epithelial metabolic coupling
- Gemma Migneco
- Diana Whitaker-Menezes
- et al.
- 2014
- Cell Cycle
Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the "reverse Warburg effect": A transcriptional informatics analysis with validation
- Stephanos Pavlides
- Aristotelis Tsirigos
- et al.
- 2014
- Cell Cycle
The autophagic tumor stroma model of cancer or "battery-operated tumor growth": A simple solution to the autophagy paradox
- Ubaldo E. Martinez-Outschoorn
- Diana Whitaker-Menezes
- et al.
- 2014
- Cell Cycle
JNK1 stress signaling is hyper-activated in high breast density and the tumor stroma: Connecting fibrosis, inflammation, and stemness for cancer prevention
- Michael P. Lisanti
- Aristotelis Tsirigos
- et al.
- 2013
- Cell Cycle